2. Natural Products
  3. Marine natural products
  4. Other marine organisms

Other marine organisms

Other marine organisms (21):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N6785
    Okadaic acid 78111-17-8 99.19%
    Okadaic acid, a marine toxin, is an inhibitor of protein phosphatases (PP). Okadaic acid has a significantly higher affinity for PP2A (IC50=0.1-0.3 nM), and inhibits PP1 (IC50=15-50 nM), PP3 (IC50=3.7-4 nM), PP4 (IC50=0.1 nM), PP5 (IC50=3.5 nM), but does not inhibit PP2C. Okadaic acid increases of phosphorylation of a number of proteins by inhibiting PP, and acts a tumor promoter. Okadaic acid induces tau phosphorylation.
    Okadaic acid
  • HY-N7819
    Pristane 1921-70-6 99.87%
    Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil. Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat.
    Pristane
  • HY-16050
    Plitidepsin 137219-37-5 99.80%
    Plitidepsin (Aplidine) is a potent anti-cancer agent by targeting eEF1A2 ( KD=80 nM). Plitidepsin possesses antiviral activity and is against SARS-CoV-2 with an IC90 of 0.88 nM. Plitidepsin is usually used for multiple myeloma and advanced cancer research, and has the potential for COVID-19 research.
    Plitidepsin
  • HY-105055
    Didemnin B 77327-05-0 99.67%
    Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer.
    Didemnin B
  • HY-15580
    Dolastatin 10 110417-88-4 98.11%
    Dolastatin 10 (DLS 10) is a potent antimitotic peptide that inhibits tubulin polymerization.
    Dolastatin 10
  • HY-N6785R
    Okadaic acid (Standard) 78111-17-8
    Okadaic acid (Standard) is the analytical standard of Okadaic acid. This product is intended for research and analytical applications. Okadaic acid, a marine toxin, is an inhibitor of protein phosphatases (PP). Okadaic acid has a significantly higher affinity for PP2A (IC50=0.1-0.3 nM), and inhibits PP1 (IC50=15-50 nM), PP3 (IC50=3.7-4 nM), PP4 (IC50=0.1 nM), PP5 (IC50=3.5 nM), but does not inhibit PP2C. Okadaic acid increases of phosphorylation of a number of proteins by inhibiting PP, and acts a tumor promoter. Okadaic acid induces tau phosphorylation.
    Okadaic acid (Standard)
  • HY-126644
    Halocyamine B 122548-04-3
    Halocyamine B exhibits antimicrobial activity against a variety of bacteria and yeasts. Halocyamine B exhibits cytotoxicity to cultured neural cells of rat fetal brain, mouse neuroblastoma N18 cells, and human hepatoma HepG2 cells.
    Halocyamine B
  • HY-126744
    Juncin E 129602-22-8
    Juncin E is a diterpenoid found in the soft coral Junceella juncea that exhibits significant insecticidal activity against the larvae of two important agricultural pests: southern corn rootworm and tobacco armyworm[2].
    Juncin E
  • HY-16468
    Squalamine 148717-90-2 99.54%
    Squalamine (MSI-1256) is an aminosterol compound with broad-spectrum antiviral activity. Squalamine makes cells less conducive to certain viral replication by altering the electrostatic interactions in the inner membrane of host cells. Squalamine also has antibacterial and antitumor activities. Squalamine has broad-spectrum antibacterial activity against Gram-negative and Gram-positive bacteria, fungi and protozoa. Squalamine inhibits tumor-related angiogenesis and the growth of human breast cancer cells. Squalamine restores the function of enteric nervous system in Parkinson,s disease mouse models.
    Squalamine
  • HY-105231
    Bryostatin 1 83314-01-6 99.70%
    Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a potent and central nervous system (CNS)-permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein with Kis of 8.07 nM and 0.45 nM, respectively. Bryostatin 1 has anti-cancer, anti-inflammatory, neuroprotective, anti-HIV-1 infection properties.
    Bryostatin 1
  • HY-133968
    24-Methylenecholesterol 474-63-5 99.48%
    24-Methylenecholesterol (Ostreasterol), a natural marine sterol, stimulates cholesterol acyltransferase in human macrophages. 24-Methylenecholesterol possess anti-aging effects in yeast. 24-methylenecholesterol enhances honey bee longevity and improves nurse bee physiology.
    24-Methylenecholesterol
  • HY-16467
    Squalamine lactate 320725-47-1 98.27%
    Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity, and used for the treatment of neovascular age-related macular degeneration.
    Squalamine lactate
  • HY-13626
    Spisulosine 196497-48-0 99.00%
    Spisulosine (ES-285) is an antiproliferative (antitumoral) compound of marine origin. Spisulosine inhibits the growth of the prostate PC-3 and LNCaP cells through intracellular ceramide accumulation and PKCζ activation.
    Spisulosine
  • HY-124550
    Sarcophine 55038-27-2
    Sarcophine ((+)-Sarcophine) is a potent glycine receptor (GlyR) inhibitor with an IC50 value of 3.9 μM. Sarcophine is a nature product that could be isolated form the Red Sea soft coral Sarcophyton glaucum.
    Sarcophine
  • HY-126594
    Echinoside B 75410-52-5
    Echinoside B is a antifungal oligoglycosides isolated from Sea Cucumber Actinopyga echinites.
    Echinoside B
  • HY-155851
    Lepadin E 444914-19-6
    Lepadin E is a significantly cytotoxic ferroptosis inducer that induces iron death through the classical p53-SLC7A11-GPX4 pathway. Lepadin E promoted p53 expression, decreases SLC7A11 and GPX4 levels, and leads to increased ROS and lipid peroxide production, and upregulated ACSL4 expression, thus causes cell death. Lepadin E has significant antitumor effect.
    Lepadin E
  • HY-155852
    Lepadin H 412328-25-7
    Lepadin H is a marine alkaloid and ferroptosis inducer. Lepadin H exhibits significant cytotoxicity, promotes p53 expression, increases ROS production and lipid peroxidation, decreases SLC7A11 and GPX4 levels, and upregulates ACSL4 expression. Lepadin H induces ferroptosis through the p53-SLC7A11-GPX4 pathway.
    Lepadin H
  • HY-N11667
    18-O-Demethylpederin 2120362-33-4
    18-O-Demethylpederin is a pederin analogue. Pederin is a natural polyketide compound extracted from Paederus for the first time. It is a non-protein insect toxin with a broad spectrum of biological activities, including antibacterial, antiviral, and antitumor.
    18-O-Demethylpederin
  • HY-N7569
    Demethoxyfumitremorgin C 111768-16-2
    Demethoxyfumitremorgin C is a secondary metabolite of the marine fungus, Aspergillus fumigatus. Demethoxyfumitremorgin C induces prostate cancer cell apoptosis. Demethoxyfumitremorgin C activates caspase-3, -8, and -9, leading to PARP/ cleavage.
    Demethoxyfumitremorgin C
  • HY-162556
    (+)-Desmethylxestospongin B 144789-03-7
    (+)-Desmethylxestospongin B ((+)-dmXeB) is a potent antagonist of inositol triphosphate receptor (IP3R), leading to cellular autophagy and allowing selective tumor cell apoptosis.
    (+)-Desmethylxestospongin B